Every year, the Scientific Meetings go over any acquired knowledge on one skin cell. Mornings are reserved for fondamental approaches, while afternoons are devoted to approaches applied to physiopathology, pharmacology and therapeutic. These are multi-subject meetings. Each presentation starts with a general overview of the terminology used, and continues with the speaker's own research. All participating members receive a commented bibliography that you may soon refer to on this site. The cycle covers approximately a 10 year period. The new scientific day will be held in November 16, 2007 and will be devoted to "Angio- and lymphangio-genesis in skin physiology and disease". You may soon refer to the presentations' program on this site.

Journées scientifiques

Previously held Scientific Days : Click onthetheme ofthe day to viewthe list of speakers SCIENTIFIC MEETING 2007 : ANGIO- AND LYMPHANGIO-GENESIS IN SKIN PHYSIOLOGY AND DISEASE SCIENTIFIC MEETING 2006 : MOLECULAR AND CLINICAL ASPECTS OF MELANOCYTE DIFFERENTIATION, GROWTH AND FUNCTIONING SCIENTIFIC MEETING 2005 : IN DEFENCE OF THE EPIDERMIS SCIENTIFIC MEETING 2004 : THE KERATINOCYTE: INTER AND EXTRACELLULAR EVENTS SCIENTIFIC MEETING 2003 : T-CELLS AND THE SKIN IMMUNE SYSTEM SCIENTIFIC MEETING 2002 : T-Cells and the skin immune system SCIENTIFIC MEETING 2001 : Neurophysiology of the skin SCIENTIFIC MEETING 2000 : Mast cell SCIENTIFIC MEETING 1999 : Extracellular matrix SCIENTIFIC MEETING 1998 : Fibroblast SCIENTIFIC MEETING 1997 : The endothelial cell SCIENTIFIC MEETING 1996 : Melanocyte SCIENTIFIC MEETING 1995 : Keratinocyte in proliferation SCIENTIFIC MEETING 1994 : Keratinocyte in differenciation SCIENTIFIC MEETING 1993 : Pharmacological modulation of Langerhans'cell functions SCIENTIFIC MEETING 1993 : PHARMACOLOGICAL MODULATION OF LANGERHANS' CELL FUNCTIONS Friday 5th november 1993, PARIS. Ministère de l’Education Nationale - Amphithéâtre Poincaré, 1, rue Descartes, 75005 Paris.   STINGL Georges Langerhans' cell and antigen presentation. HANAU Daniel Langerhans' cell and endocytosis SCHULLER Gerold Epidermal Langerhans' cell as a model to studythe biology of denditric cells. DUBERTRET Louis et de PROST Yves Presentation ofthe Fondation René Touraine. SCHMITT Daniel Critical studies of in vitro models available for studying Langerhans' cell functions. BANCHEREAU Jacques Biological functions of Langerhans' cell generated in vitro from hematopoïetic progenitors. BIEBER Thomas Langerhans' cell and lgE. DEGITZ Klaus Immunologic adhesion molecules ofthe skin.   Langerhans' cell and vitamin D3 derivatives. BAGOT Martine Role of Langerhans' cell in nickel - specific contact dermatitis. Oral induction of immune tolerance. BERGSTRESSER Paul Modulation of Langerhans' cells functions by UV light. Back to top SCIENTIFIC MEETING 1994 : KERATINOCYTE IN DIFFERENCIATION Friday 4th november 1994, PARIS. Ministère de l’Education Nationale - Amphithéâtre Poincaré, 1, rue Descartes, 75005 Paris.   GREEN Howard New trends in epidermal differenciation. BARRANDON Yann Epidermal stem cells. LEIGH Irène Keratins in differenciation. PROCKSCH Ehrhardt Terminal differenciation terminale of the stratum corneum and formation of the epidermal permeability barrier. BASSET Nicole cFos, calcium and keratinocyte differenciation. ROOP Denis Molecular genetics and keratinization. SARASIN Alain U.V. Carcinogenesis : what is the best cellular model ? BICKLE Daniel Vitamin D and keratinocyte differenciation. BLUMENBERG Miroslav Retinoids and keratinocyte differenciation. FUSENIG Norbert Growth factors and keratinocytes. Back to top SCIENTIFIC MEETING 1995 : KERATINOCYTE IN PROLIFERATION Friday 17th november 1995, PARIS. Ministère de l’Education Nationale - Amphithéâtre Poincaré, 1, rue Descartes, 75005 Paris.   BRECHOT Christian Cell cycle and its control. DIVE Caroline The apoptose. YUSPA Stuart Epidermal carcinogenesis. WATT Fiona Control of epidermal cell proliferation and differenciation. COULOMB Bernard Dermal control of epidermal growth. LUGER Thomas Cytokines and neurohormones : regulatory role in inflammation and keratinocyte proliferation. KRUEGER Gerald Is psoriasis a keratinocyte disease ? FERGUSSON Marc Wound healing : the control of epithelialisation and scarring. Back to top SCIENTIFIC MEETING 1996 : MELANOCYTE Friday 25th october 1996, PARIS. Ministère de l’Education Nationale - Amphithéâtre Poincaré, 1, rue Descartes, 75005 Paris. ZILLER Catherine Melanocytes migration and differenciation during embryogenesis. HEARING Vincent Genetic control of pigmentation. BALLOTTI Robert Melanins and melanogenesis : a perspective look. THODY Anthony Neuro-hormonal control of pigmentation. de LUCAS Michele Keratinocytes/melanocytes interactions. ORTONNE J.P. Immunology of melanocyte. FRIEDMANN Peter Photoregulation of pigmentation. HILL Helen Z. Melanines and photoprotection. Back to top SCIENTIFIC MEETING 1997 : THE ENDOTHELIAL CELL Friday 14th november 1997, PARIS. Ministère de l’Education Nationale - Amphithéâtre Poincaré, 1, rue Descartes, 75005 Paris.   L. DROUET Endothelial cells :questions for to day and tomorrow. P. PETZLBAUER Angiogenesis and adherens junction proteins. D. de PROST Coagulation tissue factor and endothelial cells. K. ALITALO Vascular growth factors and receptors in angiogenesis. T. LUGER Neuropeptides and endothelial cells. E. TSCHACHLER Keratinocytes and microcirculation. R. BICKNELL Vascular targeting of anticancer gene therapy T. LAWLEY Endothelial cells and inflammation. H. LU Proteases of endothelial cell and the regulation of angiogenesis. Back to top SCIENTIFIC MEETING 1998 : FIBROBLAST Friday 12th november 1998, PARIS. Ministère de l’Education Nationale - Amphithéâtre Poincaré, 1, rue Descartes, 75005 Paris.   C. LAPIERE The Fibroblast and its functions. C. GRIFFITHS Cellular and molecular events in photoageing. J. VARANI Modulation of fibroblast functions by retinoids. A. DESMOULIERE The myofibroblast. S. WERNER Fibroblast/keratinocyte interactions. T. KRIEG Scleroderma. M. JALKANEN Wound-induced syndecan-1 upregulation : how and why ? S. PINNELL Antifibrotic drug development. J. DAVIDSON Gene therapy for tissue repair.   Back to top SCIENTIFIC MEETING 1999 : EXTRACELLULAR MATRIX Friday 12th november 1998, PARIS. Ministère de l’Education Nationale - Amphithéâtre Poincaré, 1, rue Descartes, 75005 Paris.   C. PIERARD Dermal architecture. H. GARONNE Collagens : structures and functions. W. HORNEBECK Elastin and elastic fibers. V.-M. KAHARI Matrix metalloproteinases in skin. A. SONNENBERG Integrins : attachment structures and matrix receptors. A. CAPLAN The proteoglycans and cells of the dermis. A. MAUVIEL TGF-B signaling by the Smad pathway. D. PROCKOP Parmacological control of collagen synthesis. F.-X. MAQUART Cytokines and extracellular matrix remodeling. Back to top SCIENTIFIC MEETING 2000 : MAST CELL Friday 10th November 2000, in Paris, au Ministère de la Recherche et de la Technologie. Amphithéâtre Poincaré, 1, rue Descartes, 75005 - Paris.   A. DVORAK Introduction to cutaneous mast cells physiology and ultrastructure. F. LEVI-SCHAFFER Growth factors and survival of cutaneous mast cells. J. BIENENSTOCK significance of neuroimmune interactions in the skin: conceptual and practical issues. P. VALENT Expression of CD antigens in human mast cells. M. CHURCH Pharmacological modulation of mast cell function. B. KAY Mast cells and basophils in human cutaneous allergic tissue reactions. B. HENZ Mast cells and urticaria. M. AROCK Mastocytosis. Back to top SCIENTIFIC MEETING 2001:NEUROPHYSIOLOGY OF THE SKIN Thursday 15th November 2001, in Paris, au Ministère de la Recherche et de la Technologie. Amphithéâtre Poincaré, 1, rue Descartes, 75005 Paris.   E. DUPIN Embryogenesis of neuro-epithelial interactions D. METZE Functional anatomy of the skin nervous system T. LUGER Neuroimmunology H.O. HANDWERKER Neuromediators, pruritus and pain 0J. ANSEL Neuromediators and inflammation Z. ABDEL-MALEK Neuromediators and pigmentation R. PAUS Stress and skin N.W. BUNNETT Pharmacological modulation of skin neuromediators (PAR II) Back to top SCIENTIFIC MEETING 2002 : T-CELLS AND THE SKIN IMMUNE SYSTEM Thursday 14th November 2002, in Paris, au Ministère de la Recherche et de la Technologie. Amphithéâtre Poincaré, 1, rue Descartes, 75005 Paris.   G. STINGL Skin immune system overview C. ROBERT Homing receptors: potential therapeutical tools ? P. LOETSCHER Chemokines and their receptors in T-cell migration F. SALLUSTO The role of chemokine receptors in primary, effector and memory immune responses S. GRABBE Role of integrins in T-cell trafficking S. BULFONE-PAUS Exploring the role of IL-15 in the skin immune system R. DUMMER CTCL - a tumour of skin homing T-cells J. CARBALLIDO Therapeutic modification of leukocyte homing to the skin Back to top SCIENTIFIC MEETING 2003:T-CELLS AND THE SKIN IMMUNE SYSTEM Friday 7th November 2003, in Paris,au Ministère de la Recherche et de la Technologie. Amphithéâtre Poincaré, 1, rue Descartes, 75005 Paris.   H. VON BOEHMER T cell development A. TRAUTMANN The immunological synapse between T E. SHEVACH Control of T cell responses by regulatory/ suppressor T cells. E. VIVIER Biology of NKR+-T cells S. BEISSERT T cells in cutaneous autoimmunity M. AKDIS T cell responses in atopic eczema J. PRINZ T cells in psoriasis H. BACHELEZ Immunotherapy by targeting T cells Back to top SCIENTIFIC MEETING 2004: THE KERATINOCYTE: INTER AND EXTRACELLULAR EVENTS Friday 5th November 2004, in Paris,au Ministère de la Recherche et de la Technologie. Amphithéâtre Poincaré, 1, rue Descartes, 75005 Paris.   D. GARROD Intercellular junctions in normal epidermis M. JONKMAN Dysfunction of keratinocyte adhesion D. PROWSE Developmental signals in skin morphogenesis suppressor T cells. Y. BARRANDON Keratinocyte stem cells. Is stem plasticity a likely contribution? T. MAGIN Animal models of human skin disease D. KELSELL Connexin mutations in human disease L. BRUCKNER-TUDERMAN Inherited and acquired diseases of basement membrane – potential for therapy I. HART Role of integrins in tumour invasion and metastasis Back to top SCIENTIFIC MEETING 2005: IN DEFENCE OF THE EPIDERMIS Thursday 10 th November, in Paris, au Ministère de l’Education Nationale, de l’Enseignement Supérieure et de la Recherche. Amphithéâtre Poincaré, 1, rue Descartes, 75005 Paris.   P. ELIAS Introduction to barrier function D. HOHL Formation of the cornified envelope G. COURTOIS NFkB: a key regulator. J-M. SCHRÖDER The role of antimicrobial peptides and proteins in keratinocyte defence S. WERNER Dermal-epidermal interactions T. SCHWARZ Biological effects of the UV on keratinocytes and Langerhans cells E. TSCHACHLER Apoptotic pathways in the epidermis I. LEIGH Genetic diseases affecting the epidermis H. PFISTER Modifications of keratinocyte functions by Human Papilloma Viruses Back to top SCIENTIFIC MEETING 2006: MOLECULAR AND CLINICAL ASPECTS OF MELANOCYTE DIFFERENTIATION, GROWTH AND FUNCTIONING Friday 10 th November, in Paris, au Ministère de l’Education Nationale, de l’Enseignement Supérieure et de la Recherche. Amphithéâtre Poincaré, 1, rue Descartes, 75005 Paris.   C. GODING Melanocyte proliferation E. STEINGRIMSSON The Mitf transcription factor in melanocyte development K.C. CHENG Surprise insights into human pigmentation from zebrafish D. BENNETT Melanocyte senescence J.L. REES The genetics of skin and hair pigmentation in man K. SMALLEY Is knowledge about the genetics and epigenetic alteration in melanoma a basis for targeted therapy? A. SARASIN Melanoma gene expression profiling G. de SAINT BASILE Griscelli-Prunieras syndrome/melanosome transport R.A. SPRITZ The genetics of Vitiligo SCIENTIFIC MEETING 2007: ANGIO- AND LYMPHANGIO-GENESIS IN SKIN PHYSIOLOGY AND DISEASE Friday 16th November 2007, in Paris, au Musée des Moulages de l’Hôpital Saint-Louis 1 avenue Claude Vellefaux – 75010 Paris .   M. DEWERCHIN Functional genomics to study K. ALITALO Lymphangiogenesis in development and human disease M. DETMAR Angiogenesis and lymphangiogenesis in cutaneous C. BOSHOFF Kaposi sarcoma, KSHV and lymphangiogenesis D.M. McDONALD Cellular actions of angiogenesis inhibitors on blood